Pui Pik Law

Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study

Vincenzo Libri, Cihangir Yandım, Stavros Athanasopoulos et al. · The Lancet · 2014 · 147 citations · Full text

Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3

Paul K.S. Chan, Raul M. Torres, Pui Pik Law et al. · Human Molecular Genetics · 2013 · 78 citations · Full text

Epigenetic Change, Genetics, Vitamin B3 +19

Ras activation in normal white blood cells and childhood acute lymphoblastic leukemia.

Friederike C. von Lintig, Ivana Huvar, Pui Pik Law et al. · PubMed · 2000 · 61 citations

Hematological Malignancy, Autoimmune Disease, Mixed-phenotype Acute Leukemia +11

TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres

Rosa María Porreca, Emilia Herrera‐Moyano, Eleni Skourti et al. · eLife · 2020 · 41 citations · Full text

Genetics, Genomic Mechanism, Molecular Biology +16

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

Francisco Rodríguez-Algarra, Robert A. Seaborne, Amy F. Danson et al. · Genome biology · 2022 · 35 citations · Full text