Gehad Lotfy

Synthesis of new spirooxindole-pyrrolothiazole derivatives: Anti-cancer activity and molecular docking

Gehad Lotfy, Mohamed M. Said, El Sayed H. El Ashry et al. · Bioorganic & Medicinal Chemistry · 2017 · 73 citations

Molecular Docking, Combinatorial Chemistry, Medicinal Chemistry +9

Synthesis and structure investigation of novel pyrimidine-2,4,6-trione derivatives of highly potential biological activity as anti-diabetic agent

Assem Barakat, Saied M. Soliman, Abdullah Mohammed Al‐Majid et al. · Journal of Molecular Structure · 2015 · 70 citations

Structure Investigation, Biochemistry, Medicine +7

Regio- and stereoselective synthesis of new spirooxindoles via 1,3-dipolar cycloaddition reaction: Anticancer and molecular docking studies

Gehad Lotfy, El Sayed H. El Ashry, Mohamed M. Said et al. · Journal of Photochemistry and Photobiology B Biology · 2018 · 52 citations

Combinatorial Chemistry, Molecular Docking Studies, Medicinal Chemistry +11

Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators

Gehad Lotfy, Yasmine M. Abdel Aziz, Mohamed M. Said et al. · Bioorganic Chemistry · 2021 · 49 citations · Full text

Molecular Hybridization Design, Medicine, Rational Drug Design +4

Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling Attenuation

Yasmine M. Abdel Aziz, Gehad Lotfy, Mohamed M. Said et al. · Frontiers in Chemistry · 2021 · 41 citations · Full text