Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason, +345

Nature Communications

Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer

Antonela Merlotti, Benjamin Sadacca, Yago A. Arribas, +19

Science Immunology

Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis

Michel Wassef, Verónica Rodilla, Aurélie Teissandier, +20

Genes & Development

Histone ModificationsBreast OncologyCancer BiologyEpigeneticsTumor Biology +15

Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements

Marianne Burbage, Ares Rocañín-Arjó, Blandine Baudon, +20

Science Immunology

Lymphovascular invasion after neoadjuvant chemotherapy is strongly associated with poor prognosis in breast carcinoma

Anne‐Sophie Hamy, Giang-Thanh Lam, Enora Laas, +15

Breast Cancer Research and Treatment

Surgical OncologyBreast OncologyMedicinePathologyBreast Cancer +6

Biological network-driven gene selection identifies a stromal immune module as a key determinant of triple-negative breast carcinoma prognosis

Hélène Bonsang‐Kitzis, Benjamin Sadacca, Matahi Moarii, +3

OncoImmunology

No evidence for TSLP pathway activity in human breast cancer

Cristina Ghirelli, Benjamin Sadacca, Fabien Reyal, +9

OncoImmunology

Breast OncologySignal TransductionImmunotherapyTslp Pathway ActivityTslp-tslpr Pathway Activity +12

Transposable element exonization generates a reservoir of evolving and functional protein isoforms

Yago A. Arribas, Blandine Baudon, Maxime Rotival, +18

Cell

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion

Olivier Saulnier, Katia Guedri, Marie-Ming Aynaud, +18

Nucleic Acids Research

GeneticsRna SplicingMolecular GeneticsGene Regulatory NetworkSplicing Variant +16

Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data

J. Abécassis, Anne‐Sophie Hamy, Cécile Laurent, +4

PLoS ONE

PathologyCancer RegistrationTumor BiologyOvarian CancerOncology +16