Philipp Treskes

Human Hepatic Hepa<scp>RG</scp> Cells Maintain an Organotypic Phenotype with High Intrinsic <scp>CYP</scp>450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic Applications

Leonard J. Nelson, Katie Morgan, Philipp Treskes et al. · Basic & Clinical Pharmacology & Toxicology · 2016 · 67 citations · Full text

Medicine, Cell Biology, Pharmacology +15

Chlorpromazine toxicity is associated with disruption of cell membrane integrity and initiation of a pro-inflammatory response in the HepaRG hepatic cell line

Katie Morgan, Nicole J. Martucci, Ada Kozlowska et al. · Biomedicine & Pharmacotherapy · 2019 · 48 citations · Full text

Medicine, Pharmacology, Toxicology +16

Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model

Leonard J. Nelson, María Á. Navarro, Philipp Treskes et al. · Scientific Reports · 2015 · 47 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver

Wesam Gamal, Philipp Treskes, Kay Samuel et al. · Scientific Reports · 2017 · 42 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Profiling the Impact of Medium Formulation on Morphology and Functionality of Primary Hepatocytes in vitro

Leonard J. Nelson, Philipp Treskes, A. Forbes Howie et al. · Scientific Reports · 2013 · 26 citations · Full text

Medicine, Biochemistry, Bioengineering +17