A unique squalenoylated and nonpegylated doxorubicin nanomedicine with systemic long-circulating properties and anticancer activity

Andrei Maksimenko, Franco Dosio, Julie Mougin, +9

Proceedings of the National Academy of Sciences

NanomedicineMedicinal ChemistryEngineeringSystemic Long-circulating PropertiesPolymer-drug Conjugate +12

In Vitro and In Vivo Efficacy of Photofrin® and Pheophorbide a, a Bacteriochlorin, in Photodynamic Therapy of Colonic Cancer Cells¶

Amor Hajri, Séverine Wack, Cindy Meyer, +4

Photochemistry and Photobiology

PhotobiologyVivo EfficacyPdt EfficacyTumor BiologyPhototoxicity +15

K‐ras oncogene silencing strategy reduces tumor growth and enhances gemcitabine chemotherapy efficacy for pancreatic cancer treatment

Soukaina Réjiba, Séverine Wack, Marc Aprahamian, +1

Cancer Science

Design, optimization and in vitro evaluation of reverse micelle-loaded lipid nanocarriers containing erlotinib hydrochloride

Sandy Vrignaud, J. Hureaux, Séverine Wack, +2

International Journal of Pharmaceutics

Lipid PreparationNanomedicineMedicinal ChemistryEngineeringMedicine +7

Improving the Antitumor Activity of Squalenoyl‐Paclitaxel Conjugate Nanoassemblies by Manipulating the Linker between Paclitaxel and Squalene

Joachim Caron, Andrei Maksimenko, Séverine Wack, +6

Advanced Healthcare Materials

NanoparticlesSqualenoyl‐paclitaxel Conjugate NanoassembliesNanotherapeuticsAntitumor ActivityEngineering +16

Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines

Chantal Schwartz, Valérie Palissot, Nasséra Aouali, +5

International Journal of Oncology

Hematological MalignancyValproic AcidVpa TreatmentMedicineMalignant Blood Disorder +12

Squalenoyl nucleoside monophosphate nanoassemblies: New prodrug strategy for the delivery of nucleotide analogues

Joachim Caron, L. Harivardhan Reddy, Sinda Lepêtre‐Mouelhi, +6

Bioorganic & Medicinal Chemistry Letters

NanomedicineMedicinal ChemistryEngineeringBiochemistryPolymer-drug Conjugate +7

Feasibility, sensitivity, and reliability of laser-induced fluorescence imaging of green fluorescent protein-expressing tumors in vivo

Séverine Wack, Amor Hajri, F. Heisel, +5

Molecular Therapy

Gfp ExpressionTissue ImagingEngineeringOncologic ImagingGfp Imaging Procedure +12

Squalenoyl Gemcitabine Monophosphate: Synthesis, Characterisation of Nanoassemblies and Biological Evaluation

Joachim Caron, Élise Lepeltier, L. Harivardhan Reddy, +5

European Journal of Organic Chemistry

Supramolecular AssemblyNanotherapeuticsEngineeringChemical BiologyProtein Nanoparticles +20

Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes

Amor Hajri, Séverine Wack, Pierre Lehn, +4

Cancer Gene Therapy

Suicide Gene TherapyPancreatic Peritoneal CarcinomatosisPancreatic CancerBgtc LiposomesGastrointestinal Oncology +5