Yangchun Ma

Exploring the cause of the inhibitor 4AX attaching to binding site disrupting protein tyrosine phosphatase 4A1 trimerization by molecular dynamic simulation

Weiya Li, Yuqing Duan, Yangchun Ma et al. · Journal of Biomolecular Structure and Dynamics · 2019 · 22 citations

Protein Assembly, Ptp4a1 Trimerization, Molecular Biology +16

Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5<i>H</i>)-furanone Derivatives as Potent Quorum Sensing Inhibitors

Panpan Zhang, Weijin Chen, Yangchun Ma et al. · Journal of Medicinal Chemistry · 2023 · 18 citations · Full text

Identification of protein tyrosine phosphatase 1B (PTP1B) inhibitors through De Novo Evoluton, synthesis, biological evaluation and molecular dynamics simulation

Jingwei Wu, Yangchun Ma, Hui Zhou et al. · Biochemical and Biophysical Research Communications · 2020 · 17 citations

De Novo Evoluton, Drug Target, Biochemistry +12

Design, synthesis, biological evaluation and molecular dynamics simulation studies of imidazolidine-2,4-dione derivatives as novel PTP1B inhibitors

Yangchun Ma, Tingting Ding, Ya-Ya Liu et al. · Biochemical and Biophysical Research Communications · 2021 · 13 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +11

New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes

Yangchun Ma, Xiaohong Chang, Shenyan Zhang et al. · European Journal of Medicinal Chemistry · 2023 · 12 citations

Medicinal Chemistry, Ftsz Polymerization, Dual-targeting Mechanism +8