Ming‐Chen Chou

A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment

Jen‐Shin Song, Chih-Chun Chang, Chien-Huang Wu et al. · Proceedings of the National Academy of Sciences · 2021 · 86 citations · Full text

Discovery of 2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1<i>H</i>-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an Active Metabolite. A Novel, Potent and Selective Cannabinoid-1 Receptor Inverse Agonist with High Antiobesity Efficacy in DIO Mice

Chien-Huang Wu, Ming‐Shiu Hung, Jen‐Shin Song et al. · Journal of Medicinal Chemistry · 2009 · 42 citations · Full text

Discovery of 1-(2,4-Dichlorophenyl)-<i>N</i>-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5-(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1<i>H</i>-pyrazole-3-carboxamide as a Novel Peripherally Restricted Cannabinoid-1 Receptor Antagonist with Significant Weight-Loss Efficacy in Diet-Induced Obese Mice

Chun‐Ping Chang, Chien-Huang Wu, Jen‐Shin Song et al. · Journal of Medicinal Chemistry · 2013 · 36 citations

Drug Target, Novel Peripherally, Pharmacotherapy +25

HMDS-promotedin situ amidation reactions of car☐ylic acids and amines

Wen‐Chih Chou, Ming‐Chen Chou, Yann‐Yu Lu et al. · Tetrahedron Letters · 1999 · 28 citations

Engineering, Organic Chemistry, Derivative (Chemistry) +3

Stem Cell Mobilizers Targeting Chemokine Receptor CXCR4: Renoprotective Application in Acute Kidney Injury

Chien-Huang Wu, Jen‐Shin Song, Kuei-Hua Chang et al. · Journal of Medicinal Chemistry · 2015 · 23 citations