Measuring affinity constants of 1450 monoclonal antibodies to peptide targets with a microarray-based label-free assay platform

J. P. Landry, Yaohuang Ke, Guo-Liang Yu, +1

Journal of Immunological Methods

MedicineNatural SciencesBioanalysisMass SpectrometryImmunology +9

Effect of Fluorescently Labeling Protein Probes on Kinetics of Protein−Ligand Reactions

Yung-Shin Sun, J. P. Landry, Y. Y. Fei, +4

Langmuir

Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical reactions in a microarray format

X. D. Zhu, J. P. Landry, Yung-Shin Sun, +3

Applied Optics

EngineeringMicroscopyMolecular BiologyMicroarray FormatMicroscope Slide +16

Simultaneous Measurement of 10,000 Protein-Ligand Affinity Constants Using Microarray-Based Kinetic Constant Assays

J. P. Landry, Yiyan Fei, X. D. Zhu

Assay and Drug Development Technologies

Molecular DockingBiochemistryFluorescence-based Endpoint DetectionMedicineNatural Sciences +13

Label-free detection of microarrays of biomolecules by oblique-incidence reflectivity difference microscopy

J. P. Landry, X. D. Zhu, J. Gregg

Optics Letters

EngineeringMicroscopyOligonucleotide MicroarrayMolecular BiologyLabel-free Detection +15

Fluorescent labeling agents change binding profiles of glycan-binding proteins

Yiyan Fei, Yung-Shin Sun, Yanhong Li, +7

Molecular BioSystems

A novel high-throughput scanning microscope for label-free detection of protein and small-molecule chemical microarrays

Y. Y. Fei, J. P. Landry, Yung-Shin Sun, +4

Review of Scientific Instruments

EngineeringMicroscopyOptical MicroscopeDna MicroarraysMolecular Biology +18

Protein reactions with surface-bound molecular targets detected by oblique-incidence reflectivity difference microscopes

J. P. Landry, Yung-Shin Sun, Xiaowen Guo, +1

Applied Optics

EngineeringMicroscopyMolecular BiologyLight Scattering SpectroscopySurface Mass Density +14

Macromolecular Scaffolds for Immobilizing Small Molecule Microarrays in Label-Free Detection of Protein−Ligand Interactions on Solid Support

Yung-Shin Sun, J. P. Landry, Yu-Huai Fei, +4

Analytical Chemistry

EngineeringSmall Molecule CompoundsMolecular BiologyBiofabricationProtein−ligand Interactions +18

Incidence-angle dependence of optical reflectivity difference from an ultrathin film on solid surface

J. P. Landry, Joseph N. Gray, Martina O’Toole, +1

Optics Letters

Optical MaterialsEngineeringOptical GlassUltrathin FilmsOptical Properties +15