Derek L. Bolhuis - Concepedia

Author

Derek L. Bolhuis

University of North Carolina at Chapel Hill ORCID

Also Known As

Bolhuis, Derek L., Brown, Nicholas G., Cui, Liying, Das, Sudipto, Derek L Bolhuis, Derek L. Bolhuis, Gibbs, Morgan E., Temple, Brenda R S, Toomer, E Drew, Xu, Xia

Publications

310

Citations

H-Index

Concepts

All Affiliations

University of North Carolina at Chapel Hill UNC Lineberger Comprehensive Cancer Center Research Institute of Molecular Pathology Medical University of Vienna Vienna Biocenter

About

Derek L. Bolhuis is an author at University of North Carolina at Chapel Hill specializing in medicine, natural sciences, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	51
2	Natural Sciences	2	2	41
3	Cell Biology	2	2	29
4	Molecular Biology	2	2	53
5	Biomolecular Engineering	1	1	34

Derek L. Bolhuis

Publications

265

Citations

H-Index

Page 1

	Year	Citations
Cryo‐EM structure of the chain‐elongating E3 ubiquitin ligase UBR5 Zuzana Hodáková, Irina Grishkovskaya, Hanna L. Brunner, The EMBO Journal	2023	41
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming Raquel C. Martinez‐Chacin, Tatyana Bodrug, Derek L. Bolhuis, Nature Structural & Molecular Biology Protein FunctionMolecular RegulationProtein BiosynthesisMolecular BiologySubstrate Priming	2020	34
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site Edmond R. Watson, Christy R. Grace, Wei Zhang, Proceedings of the National Academy of Sciences	2019	32
Examining the mechanistic relationship of <scp>APC</scp>/<scp>C<sup>CDH1</sup></scp> and its interphase inhibitor <scp>EMI1</scp> Derek L. Bolhuis, Raquel C. Martinez‐Chacin, Kaeli A. Welsh, Protein Science	2022	32
Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase Sabrina E. Iskandar, Jarrett M. Pelton, Elizaveta T. Wick, Journal of the American Chemical Society	2023	30
AtomNet-Aided OTUD7B Inhibitor Discovery and Validation Jianfeng Chen, Derek L. Bolhuis, Christian Laggner, Cancers Otud7b InhibitorMedicinal ChemistryDrug TargetPharmaceutical ChemistryMedicine	2023	22
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators Jennifer L. Franks, Raquel C. Martinez‐Chacin, Xianxi Wang, PLoS Biology Histone ModificationsEpigenetic ChangeGeneticsMolecular BiologyCell Cycle	2020	19
Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes Kaeli A. Welsh, Derek L. Bolhuis, Anneroos E Nederstigt, The EMBO Journal	2021	15
Cryo-EM structure of the plant 26S proteasome Susanne Kandolf, Irina Grishkovskaya, Katarina Belačić, Plant Communications	2022	15
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C) Tatyana Bodrug, Kaeli A. Welsh, Derek L. Bolhuis, Nature Structural & Molecular Biology	2023	15

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