Anna Hovhannisyan

Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition

Simon Hayek, Nicolas Pietrancosta, Anna Hovhannisyan et al. · European Journal of Medicinal Chemistry · 2019 · 20 citations · Full text

Biosynthesis, Signal Transduction, Bioorganic Chemistry +12

A new series of N5 derivatives of the 1,1,5-trimethyl furo[3,4-c]pyridine-3,4-dione (cerpegin) selectively inhibits the post-acid activity of mammalian 20S proteasomes

The Hien Pham, Anna Hovhannisyan, Dominique Bouvier et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 19 citations

N5 Derivatives, Medicinal Chemistry, Bioorganic Chemistry +6

New C4- and C1-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform

Anna Hovhannisyan, The Hien Pham, Dominique Bouvier et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 19 citations · Full text

Site-specific Inhibition, Medicinal Chemistry, Biochemistry +8

C1 and N5 derivatives of cerpegin: Synthesis of a new series based on structure–activity relationships to optimize their inhibitory effect on 20S proteasome

Anna Hovhannisyan, The Hien Pham, Dominique Bouvier et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 14 citations · Full text

N5 Derivatives, Biochemistry, Natural Sciences +8