Reid von Borstel

Metabolism of cytidine (5′)-diphosphocholine (cdp-choline) following oral and intravenous administration to the human and the rat

Ignacio López G.‐Coviella, J Agut, Reid von Borstel et al. · Neurochemistry International · 1987 · 62 citations

Medicine, Pharmacokinetics, Pharmacology +7

Phase I trial of PN401, an oral prodrug of uridine, to prevent toxicity from fluorouracil in patients with advanced cancer.

David P. Kelsen, J. O'Neil, Gretchen N. Schwartz et al. · Journal of Clinical Oncology · 1997 · 40 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Uridine Prodrug Improves Memory in Tg2576 and TAPP Mice and Reduces Pathological Factors associated with Alzheimer's Disease in Related Models

Joel A. Saydoff, Ana Olariu, Jin G. Sheng et al. · Journal of Alzheimer s Disease · 2013 · 35 citations

Medicine, Medicinal Chemistry, Neurobiology +17

Conjugates of COL-1 monoclonal antibody and β-D-galactosidase can specifically kill tumor cells by generation of 5-fluorouridine from the prodrug β-D-galactosyl-5-fluorouridine

Ralph Abraham, Nureddin Aman, Reid von Borstel et al. · Cell Biochemistry and Biophysics · 1994 · 29 citations

Pharmacy, Medicinal Chemistry, Oncology +16

Phase I and Pharmacologic Study of PN401 and Fluorouracil in Patients With Advanced Solid Malignancies

Manuel Hidalgo, Miguel A. Villalona‐Calero, S. Gail Eckhardt et al. · Journal of Clinical Oncology · 2000 · 29 citations

Medicine, Pharmacology, Pharmacotherapy +17