The Effects of Palmitate on Hepatic Insulin Resistance Are Mediated by NADPH Oxidase 3-derived Reactive Oxygen Species through JNK and p38MAPK Pathways

Dan Gao, Shanwei Nong, Xiuqing Huang, +7

Journal of Biological Chemistry

Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity

Yuan Cao, Tao Shen, Xiuqing Huang, +11

Oncotarget

GLP-1 Inhibits High-Glucose-Induced Oxidative Injury of Vascular Endothelial Cells

Quan Li, Yajun Lin, Shu Wang, +2

Scientific Reports

Lipid PeroxidationP47phox TranslocationInsulin SignalingVascular Endothelial CellsOxidative Stress +17

Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway

He Yao, Jingyu Sun, Jie Wei, +3

Frontiers in Pharmacology

Astragalus polysaccharides suppress ICAM-1 and VCAM-1 expression in TNF-α-treated human vascular endothelial cells by blocking NF-κB activation

Yuping Zhu, Tao Shen, Yajun Lin, +7

Acta Pharmacologica Sinica

Endothelial Cell PathobiologyInflammationCytokineVcam-1 ExpressionVascular Pharmacology +13

SIRT1 Functions as an Important Regulator of Estrogen-Mediated Cardiomyocyte Protection in Angiotensin II-Induced Heart Hypertrophy

Tao Shen, Ling Ding, Yang Ruan, +12

Oxidative Medicine and Cellular Longevity

Rhein lysinate suppresses the growth of breast cancer cells and potentiates the inhibitory effect of Taxol in athymic mice

Yajun Lin, Yong‐Su Zhen

Anti-Cancer Drugs

Breast OncologyChemoprevention StrategyPharmacotherapyTumor BiologyMedicinal Chemistry +18

Metformin-Induced Changes of the Coding Transcriptome and Non-Coding RNAs in the Livers of Non-Alcoholic Fatty Liver Disease Mice

Jun Guo, Yuan Zhou, Yafen Cheng, +9

Cellular Physiology and Biochemistry

Effects of rhein lysinate on D-galactose-induced aging mice

Yong‐Zhan Zhen, Yajun Lin, Kai‐Ji Li, +6

Experimental and Therapeutic Medicine

Effects of Rhein Lysinate on H2O2-induced cellular senescence of human umbilical vascular endothelial cells

Yajun Lin, Yong‐Zhan Zhen, Jie Wei, +3

Acta Pharmacologica Sinica

PhysiologyEndothelial DysfunctionCellular SenescenceVascular BiologyH2o2-induced Cellular Senescence +8