Makoto Yoneda

MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts.

Anne Chomyn, Andrea Martinuzzi, Makoto Yoneda et al. · Proceedings of the National Academy of Sciences · 1992 · 495 citations · Full text

Genetics, Molecular Biology, Mtdna Binding Site +17

Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy.

Makoto Yoneda, Anne Chomyn, Andrea Martinuzzi et al. · Proceedings of the National Academy of Sciences · 1992 · 292 citations · Full text

Mutant Genotype, Genetics, Genomic Mechanism +19

Identification of Mitochondrial DNA Polymorphisms That Alter Mitochondrial Matrix pH and Intracellular Calcium Dynamics

An-a Kazuno, Kae Munakata, Takeharu Nagai et al. · PLoS Genetics · 2006 · 225 citations · Full text

Dna, Genetics, Dna Analysis +18

Gene Therapy for Mitochondrial Disease by Delivering Restriction Endonuclease <i>Sma</i>I into Mitochondria

Masashi Tanaka, Harm-Jan Borgeld, Jin Zhang et al. · Journal of Biomedical Science · 2002 · 210 citations

Gene Therapies, Mitochondrial Function, Genetics +10

Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles.

Makoto Yoneda, T. Miyatake, Giuseppe Attardi · Molecular and Cellular Biology · 1994 · 182 citations · Full text

Dna, Genetics, Molecular Biology +17