Timon A. Bloedjes

AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

Timon A. Bloedjes, Guus de Wilde, Chiel Maas et al. · Blood Advances · 2020 · 36 citations · Full text

Life Sciences, Cell Biology, Oncology +17

The DNA Damage Response Regulates RAG1/2 Expression in Pre–B Cells through ATM-FOXO1 Signaling

Katarina Ochodnicka‐Mackovicova, Mahnoush Bahjat, Chiel Maas et al. · The Journal of Immunology · 2016 · 33 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity

Katarina Ochodnicka‐Mackovicova, Mahnoush Bahjat, Timon A. Bloedjes et al. · Blood · 2015 · 26 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors

Mahnoush Bahjat, Guus de Wilde, Tijmen van Dam et al. · Cell Cycle · 2019 · 20 citations · Full text

Medicine, Oncology, Pharmacology +17

AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

Timon A. Bloedjes, Guus de Wilde, Gerarda H. Khan et al. · Blood Advances · 2022 · 20 citations · Full text

Medicine, Cell Biology, Oncology +17