A programmable encapsulation system improves delivery of therapeutic bacteria in mice

Tetsuhiro Harimoto, Jaeseung Hahn, Yuyu Chen, +13

Nature Biotechnology

Probiotic-guided CAR-T cells for solid tumor targeting

Rosa L. Vincent, Candice R. Gurbatri, Fangda Li, +12

Science

Chimeric Antigen ReceptorCell-based Drug DeliveryEngineeringMedicineImmunology +13

Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity

Thomas Savage, Rosa L. Vincent, Sarah S. Rae, +8

Science Advances

Probiotic neoantigen delivery vectors for precision cancer immunotherapy

Andrew Redenti, Jongwon Im, Benjamin Redenti, +14

Nature

Macrophage pyroptosis is mediated by immunoproteasome subunit β5i (LMP7) in abdominal aortic aneurysm

Xu Zhang, Fangda Li, Wei Wang, +10

Biochemical and Biophysical Research Communications

InflammationApoptosisImmunologyAbdominal Aortic AneurysmPathology +8

Programmable bacteria synergize with PD-1 blockade to overcome cancer cell–intrinsic immune resistance mechanisms

Fangda Li, Zaofeng Yang, Thomas Savage, +7

Science Immunology

Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression

Marie C. Hasselluhn, Amanda R. Decker-Farrell, Lukas Vlahos, +16

Cancer Discovery

Deep Learning with Adaptive Attention for Seismic Velocity Inversion

Fangda Li, Zhenwei Guo, Xinpeng Pan, +3

Remote Sensing

Geometric LearningConvolutional Neural NetworkImage AnalysisMachine LearningData Science +11

DEBISim: A simulation pipeline for dual energy CT-based baggage inspection systems

Ankit Manerikar, Fangda Li, Avinash C. Kak

Journal of X-Ray Science and Technology