José Luís Zamora Manzano

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

Luping Lin, Amit J. Sabnis, Elton Chan et al. · Nature Genetics · 2015 · 548 citations · Full text

Medicine, Mek-targeted Cancer Therapies, Hippo Effector Yap +8

Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway

Vicenç Ruiz de Porras, Sara Bystrup, Anna Martínez‐Cardús et al. · Scientific Reports · 2016 · 131 citations · Full text

Methylation patterns and K-ras mutations in tumor and paired serum of resected non-small-cell lung cancer patients

José Luis Ramírez, Carme Sarries, Pedro López de Castro et al. · Cancer Letters · 2003 · 117 citations

Oncology, Somatic Variant, Oncogenic Agent +12

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Miguel Vizoso, Humberto J. Ferreira, Paula López-Serra et al. · Nature Medicine · 2015 · 113 citations · Full text

Medicine, Melanoma, Epigenetic Activation +5

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy

Eva Martinez‐Balibrea, Albert Abad, Anna Martínez‐Cardús et al. · British Journal of Cancer · 2010 · 88 citations · Full text

Tyms Genetic Variants, Oncology, Oncogenic Agent +8