Brian C. Mackness

Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life

Brian C. Mackness, Julie Jaworski, Ekaterina Boudanova et al. · mAbs · 2019 · 99 citations · Full text

Saturation Point Mutations, Immunology, Immune System +16

Folding of the RNA Recognition Motif (RRM) Domains of the Amyotrophic Lateral Sclerosis (ALS)-linked Protein TDP-43 Reveals an Intermediate State

Brian C. Mackness, Meme T. Tran, Shannan P. McClain et al. · Journal of Biological Chemistry · 2014 · 51 citations · Full text

Incorporation of a Reporter Peptide in FPOP Compensates for Adventitious Scavengers and Permits Time-Dependent Measurements

Ben Niu, Brian C. Mackness, Don L. Rempel et al. · Journal of the American Society for Mass Spectrometry · 2016 · 34 citations · Full text

Peptide Engineering, Biological Mass Spectrometry, Molecular Biology +23

Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models

Delphine Valente, Christine Mauriac, Thorsten Schmidt et al. · mAbs · 2020 · 28 citations · Full text

Learning the language of antibody hypervariability

Rohit Singh, Chiho Im, Yu Qiu et al. · Proceedings of the National Academy of Sciences · 2024 · 23 citations · Full text