Pauline A. Flanagan

Preclinical evaluation of polymer-bound doxorubicin

Ruth Duncan, Leonard W. Seymour, K.B. O'Hare et al. · Journal of Controlled Release · 1992 · 188 citations

Natural Sciences, Molecular Pharmaceutics, Pharmacokinetics +12

Macromolecular prodrugs for use in targeted cancer chemotherapy: melphalan covalently coupled to N- (2-hydroxypropyl) methacrylamide copolymers

Ruth Duncan, Isabella C. Hume, H. J. Yardley et al. · Journal of Controlled Release · 1991 · 68 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Immunogenicity of Protein-N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates in A/J and B10 Mice

Pauline A. Flanagan, Ruth Duncan, Vladimír Šubr et al. · Journal of Bioactive and Compatible Polymers · 1990 · 38 citations

Life Sciences, Biochemistry, Immunology +17

Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates

Pauline A. Flanagan, Pavla Kopecˇková, Jindrˇich Kopecˇek et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 1989 · 37 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Evaluation of protein-N-(2-hydroxypropyl) methacrylamide copolymer conjugates as targetable drug-carriers. 2. Body distribution of conjugates containing transferrin, antitransferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L1210 leukaemia in vivo

Pauline A. Flanagan, Ruth Duncan, Vladimír Šubr et al. · Journal of Controlled Release · 1992 · 24 citations

Pharmacy, Pharmaceutics, Pharmacology +17