Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE:  Identification and Effect on Binding Affinity

Jerry Cacia, Rodney G. Keck, Leonard G. Presta, +1

Biochemistry

Immunocytochemical TechniqueAspartic Acid ResidueImmunologyGlycobiologyMolecular Biology +21

Chemometric evaluation of on‐line high‐pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose

Tina M. Larson, Martin Gawlitzek, Heather Evans, +2

Biotechnology and Bioengineering

EngineeringAmino AcidsCell CultureHplc SystemBioanalysis +19

Use of Process Data To Assess Chromatographic Performance in Production‐Scale Protein Purification Columns

Tina M. Larson, Jeff Davis, Harry Lam, +1

Biotechnology Progress

Use of high-performance capillary electrophoresis to monitor charge heterogeneity in recombinant-DNA derived proteins

Shiaw‐Lin Wu, Glen Teshima, Jerry Cacia, +1

Journal of Chromatography A

High-performance Capillary ElectrophoresisCapillary ElectrophoresisBiochemistryMolecular Biological MethodNatural Sciences +8

Analyzing mixtures of amino acids and carbohydrates using bi-modal integrated amperometric detection

Petr Jandík, Alan P. Clarke, Nebojša Avdalović, +2

Journal of Chromatography B Biomedical Sciences and Applications

Food ChemistryEngineeringAmino AcidsBiochemistryGas Chromatography +11

The Phosphorylation of Bovine DNase I Asn-linked Oligosaccharides Is Dependent on Specific Lysine and Arginine Residues

Atsushi Nishikawa, Walter Gregory, John Frenz, +2

Journal of Biological Chemistry

Protein sorting by high-performance liquid chromatography

Jerry Cacia, Cynthia Quan, Mark Vasser, +2

Journal of Chromatography A

BiochemistryNatural SciencesMedicineBioanalysisProtein Engineering +6

Rapid method for monitoring galactosylation levels during recombinant antibody production by electrospray mass spectrometry with selective-ion monitoring

Hong Wan, Stacey Kaneshiro, John Frenz, +1

Journal of Chromatography A

Electrospray Mass SpectrometryEngineeringBiochemistryBioanalysisMass Spectrometry +12

Human DNase I Contains Mannose 6-Phosphate and Binds the Cation-Independent Mannose 6-Phosphate Receptor

Jerry Cacia, Cynthia Quan, Roger Pai, +1

Biochemistry

GlycobiologyMolecular BiologyEnzymatic ModificationNucleic Acid ChemistryProteomics +16

Protein sorting by high performance liquid chromatography. 2. Separation of isophosphorylates of recombinant human DNase I on a polyethyleneimine column

John Frenz, Cynthia Quan, Jerry Cacia, +3

Analytical Chemistry

GlycobiologyDna AnalysisMolecular BiologyRecombinant Human DnaseChemical Biology +19