Rachel C. Knopp

Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors

Taha Y. Taha, Shaimaa M. Aboukhatwa, Rachel C. Knopp et al. · ACS Medicinal Chemistry Letters · 2017 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Interaction of oxidative stress and neurotrauma in ALDH2 mice causes significant and persistent behavioral and pro-inflammatory effects in a tractable model of mild traumatic brain injury

Rachel C. Knopp, Sue Lee, Michael A. R. Hollas et al. · Redox Biology · 2020 · 24 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Amyloid Beta Pathology Exacerbates Weight Loss and Brain Cytokine Responses following Low-Dose Lipopolysaccharide in Aged Female Tg2576 Mice

Rachel C. Knopp, Kristen K. Baumann, Miranda Wilson et al. · International Journal of Molecular Sciences · 2022 · 16 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Extending the Calpain–Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma

Rachel C. Knopp, Ammar Jastaniah, Oleksii Dubrovskyi et al. · ACS Pharmacology & Translational Science · 2021 · 14 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases

Courtney R. Kent, Magdalena Bryja, Helen A. Gustafson et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11