Jan Schutrups

Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells

Alexander L. Vahrmeijer, Jan Hein van Dierendonck, Jan Schutrups et al. · Biochemical Pharmacology · 1999 · 40 citations

Medicine, Oncology, Pharmacology +17

Development of resistance to glutathione depletion-induced cell death in CC531 colon carcinoma cells: association with increased expression of Bcl-2

Alexander L. Vahrmeijer, Rob W.M. Hoetelmans, Gerard J. Mulder et al. · Biochemical Pharmacology · 2000 · 26 citations

Life Sciences, Cell Biology, Oncology +12

Lack of glutathione conjugation of melphalan in the isolated in situ liver perfusion in humans.

Alexander L. Vahrmeijer, Cor Snel, David P. T. Steenvoorden et al. · PubMed · 1996 · 16 citations

Medicine, Oncology, Pharmacology +17

Potentiation of the cytostatic effect of melphalan on colorectal cancer hepatic metastases by infusion of buthionine sulfoximine (BSO) in the rat

Alexander L. Vahrmeijer, Jan Hein van Dierendonck, Jan Schutrups et al. · Cancer Chemotherapy and Pharmacology · 1999 · 16 citations

Medicine, Oncology, Pharmacology +12