HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

Ahmed Tawakol, Parmanand Singh, Marina Mojena, +13

Arteriosclerosis Thrombosis and Vascular Biology

Direct Agonist/Antagonist Functions of Dehydroepiandrosterone

Fang Chen, Kristin Knecht, Elizabeth T. Birzin, +8

Endocrinology

Dhea SupplementationSex HormonesPharmacotherapyFemale Reproductive FunctionDhea Bound +14

A novel antiviral agent which inhibits the endonuclease of influenza viruses

Joanne E. Tomassini, M E Davies, J C Hastings, +6

Antimicrobial Agents and Chemotherapy

Novel Antiviral AgentImmunologyCell CultureAntimicrobial ChemotherapyAntiviral Drug +16

Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

Paqui G. Través, Virginia Pardo, María Pimentel-Santillana, +8

Cell Death and Disease

ImmunologyPtp1b DeficiencyCell DeathInnate ImmunityInsulin Signaling +20

Metabolic signatures linked to macrophage polarization: from glucose metabolism to oxidative phosphorylation

Lisardo Boscá, Silvia González-Ramos, Patricia Prieto, +4

Biochemical Society Transactions

Stimulatory Effect of Vasoactive Intestinal Peptide on Glycogenolysis and Gluconeogenesis in Isolated Rat Hepatocytes: Antagonism by Insulin*

Marina Mojena, Ramona A. Silvestre, Luis Monge, +1

Endocrinology

Stimulatory EffectPyruvate KinaseInsulin SignalingGastrointestinal Peptide HormoneIsolated Rat +15

Zaragozic Acids D and D₂: Potent Inhibitors of Squalene Synthase and of Ras Farnesyl-Protein Transferase

Claude Dufresne, Kenneth E. Wilson, Sheo B. Singh, +11

Journal of Natural Products

Pharmaceutical ScienceAltmetric Attention ScoreOrganic ChemistryChemical BiologyZaragozic Acids D +16

The isolation and structure elucidation of zaragozic acid C, a novel potent squalene synthase inhibitor.

Claude Dufresne, Kenneth E. Wilson, Deborah L. Zink, +15

Tetrahedron

Medicinal ChemistryBiochemistryZaragozic Acid CNatural SciencesBiocatalysis +7

Expression of the v-<i>src</i> or v-<i>fps</i> oncogene increases fructose 2,6-bisphosphate in chick-embryo fibroblasts. Novel mechanism for the stimulation of glycolysis by retroviruses

Lisardo Boscá, Marina Mojena, Jacques Ghysdael, +2

Biochemical Journal

Viral ReplicationMolecular BiologyViral Structural ProteinCellular PhysiologyFructose 2,6-Bisphosphate Suggests +17

Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3

John G. Ondeyka, Kithsiri Herath, Hiranthi Jayasuriya, +15

Molecular Diversity

Chemokine Receptor Cxcr3MedicineImmunologyReceptor (Biochemistry)Pharmacological Agent +4