Alexandre Salsmann

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

Cédric Ghevaert, Alexandre Salsmann, Nicholas A. Watkins et al. · Blood · 2007 · 98 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

A New Functional Role of the Fibrinogen RGD Motif as the Molecular Switch That Selectively Triggers Integrin αIIbβ3-dependent RhoA Activation during Cell Spreading

Alexandre Salsmann, Elisabeth Schaffner‐Reckinger, Fabrice Kabile et al. · Journal of Biological Chemistry · 2005 · 57 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Overexpression of the partially activated αIIbβ3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule‐dependent proplatelet–like extensions in Chinese hamster ovary cells

Elisabeth Schaffner‐Reckinger, Alexandre Salsmann, Najet Debili et al. · Journal of Thrombosis and Haemostasis · 2009 · 23 citations

Life Sciences, Cell Biology, Molecular Biology +12

Role of Calprotectin as a Modulator of the IL27‐Mediated Proinflammatory Effect on Endothelial Cells

Susann Antonia Dorosz, Aurélien Ginolhac, Thilo Kähne et al. · Mediators of Inflammation · 2015 · 15 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

OAG induces an additional PKC-, PI3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca2+ entry

Sabrina Bréchard, Alexandre Salsmann, Eric Tschirhart · Journal of Leukocyte Biology · 2008 · 14 citations

Life Sciences, Biochemistry, Cell Biology +16