Keith R. Mulholland - Concepedia

Concepedia

Author

Keith R. Mulholland

AstraZeneca (United Kingdom)

Also Known As

K Mulholland, K. MULHOLLAND, K. Mulholland, K. R. MULHOLLAND, Keith Mulholland, Keith R Mulholland, Keith R. Mulholland

44

Publications

1.6K

Citations

20

H-Index

37

Concepts

All Affiliations

AstraZeneca (United Kingdom)University of Manchester University of Liverpool AstraZeneca (Poland)New Frontier

KR

About

Keith R. Mulholland is an author at AstraZeneca (United Kingdom) specializing in engineering, natural sciences, and organic chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	14	16	815
2	Natural Sciences	14	15	808
3	Biochemistry	11	12	710
4	Biomolecular Engineering	11	12	668
5	Medicine	3	3	136

Keith R. Mulholland

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26

Publications

1.6K

Citations

20

H-Index

	Year	Citations
One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA), and Imine Reductase (IRED) Biocatalysts Scott P. France, Shahed Hussain, Andrew M. Hill, ACS Catalysis EngineeringChiral ImineOrganic ChemistryChemistryBiosynthesis	2016	199
A Survey of the Borrowing Hydrogen Approach to the Synthesis of some Pharmaceutically Relevant Intermediates John Leonard, A. John Blacker, Stephen P. Marsden, Organic Process Research & Development	2015	164
An (<i>R</i>)‐Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines Shahed Hussain, Friedemann Leipold, Henry Man, ChemCatChem	2015	149
Biocatalytic <i>N</i>-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades Jeremy I. Ramsden, Rachel S. Heath, Sasha R. Derrington, Journal of the American Chemical Society Carboxylic AcidsEngineeringBiochemistryReductive Aminase CascadesNatural Sciences	2019	117
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2<i>H</i>-pyran-4-yl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]quinolin-2-one) Kurt G. Pike, Bernard Barlaam, Elaine Cadogan, Journal of Medicinal Chemistry	2018	111
The Selective 5-HT<sub>1B</sub>Receptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-<i>f</i>]indole-3,4‘-piperidine] (SB-224289) Potently Blocks Terminal 5-HT Autoreceptor Function Both in Vitro and in Vivo Laramie M. Gaster, Frank E. Blaney, Susannah Davies, Journal of Medicinal Chemistry	1998	81
Biarylcarbamoylindolines Are Novel and Selective 5-HT<sub>2C</sub> Receptor Inverse Agonists: Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a Potential Antidepressant/Anxiolytic Agent Steven M. Bromidge, Steven Dabbs, David T. Davies, Journal of Medicinal Chemistry Potential Antidepressant/anxiolytic AgentPsychotropic MedicationInverse AgonistsPharmacotherapyNew Series	2000	79
Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide William R. F. Goundry, Bradley Adams, Helen Benson, Organic Process Research & Development EngineeringChemistryDesulfurizationBioprocess EngineeringBiocatalytic Process	2017	61
Bifunctional Catalysis: Direct Reductive Amination of Aliphatic Ketones with an Iridium-Phosphate Catalyst Barbara Villa‐Marcos, Chaoqun Li, Keith R. Mulholland, Molecules EngineeringIridium-phosphate CatalystOrganic ChemistryChemistryChemical Engineering	2010	56
Use of ω-Transaminase Enzyme Chemistry in the Synthesis of a JAK2 Kinase Inhibitor Lianne Frodsham, Michael Golden, Susan Hard, Organic Process Research & Development Medicinal ChemistryBiosynthesisEngineeringPharmaceutical ChemistryBiochemistry	2013	54

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