Kiyoshi Oguma

Papain Inhibitions by Optically Active E-64 Analogs

Masaharu Tamai, Kazunori Hanada, Takashi Adachi et al. · The Journal of Biochemistry · 1981 · 96 citations

Medicinal Chemistry, Natural Product Synthesis, Bioorganic Chemistry +12

Efficient synthetic method for ethyl (+)-(2S,3S)-3-((S)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylate (EST), a new inhibitor of cysteine proteinases.

Masaharu Tamai, Chihiro Yokoo, Mitsuo Murata et al. · Chemical and Pharmaceutical Bulletin · 1987 · 61 citations · Full text

Bioorganic Chemistry, Chemical Biology, Enzymatic Modification +17

Isolation of a new indole alkaloid, roquefortine D, from the cultures of Penicillium roqueforti.

Sadahiro Ohmomo, Kiyoshi Oguma, Tsutomu Ōhashi et al. · Agricultural and Biological Chemistry · 1978 · 25 citations

Biosynthesis, Bioorganic Chemistry, New Indole Alkaloid +13

Study on thiol protease inhibitors. Part IV. Relationship between structure and papain inhibitory activity of epoxysuccinyl amino acid derivatives.

Masaharu Tamai, Takashi Adachi, Kiyoshi Oguma et al. · Agricultural and Biological Chemistry · 1981 · 14 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Chemical Biology +16

Immunopharmacologic profiles of a thiol protease inhibitor, L-trans-dicyclohexyl epoxysuccinate.

Toshiro Amamoto, Tadayasu Okazaki, Toshi Komurasaki et al. · The Japanese Journal of Pharmacology · 1984 · 10 citations · Full text

Inflammation, Allergy, Autoimmune Disease +13