Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma

Vidhya M. Ravi, Paulina Will, Jan Kueckelhaus, +32

Cancer Cell

Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

Dieter Henrik Heiland, Vidhya M. Ravi, Simon P. Behringer, +18

Nature Communications

T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10

Vidhya M. Ravi, Nicolas Neidert, Paulina Will, +24

Nature Communications

Microglia contribute to the propagation of Aβ into unaffected brain tissue

Paolo d’Errico, Stephanie Ziegler‐Waldkirch, Vanessa Aires, +13

Nature Neuroscience

Human organotypic brain slice culture: a novel framework for environmental research in neuro-oncology

Vidhya M. Ravi, Kevin Joseph, Julian Wurm, +15

Life Science Alliance

Natural EnvironmentAcute Gbm SpecimensBiological MicroenvironmentsNeural Stem CellCerebral Organoid +17

Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis

Joris Guyon, Ignacio Fernández‐Moncada, Claire Larrieu, +29

EMBO Molecular Medicine

Inferring spatially transient gene expression pattern from spatial transcriptomic studies

Jan Kueckelhaus, Jasmin von Ehr, Vidhya M. Ravi, +7

EngineeringGeneticsTranscriptomics TechnologyGene CharacterizationGene Regulatory Network +18

Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma

Matthias Schneider, Lea Vollmer, Anna‐Laura Potthoff, +27

Neuro-Oncology

Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma

Julian Wurm, Simon P. Behringer, Vidhya M. Ravi, +11

Cancers

ImmunologyBiological MicroenvironmentsPurified AstrocytesGliomaTumor Biology +17

High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq

Jasim Kada Benotmane, Jan Kueckelhaus, Paulina Will, +8

Nature Communications