Molecular and cellular signatures of human vaccine adjuvants

Flaviana Mosca, Elaine Tritto, Alessandro Muzzi, +6

Proceedings of the National Academy of Sciences

ImmunologyImmunologic MechanismImmunotherapyImmune SystemInflammation +18

Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

Claudio Donati, N. Luisa Hiller, Hervé Tettelin, +15

Genome biology

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

John Donnelly, Duccio Medini, Giuseppe Boccadifuoco, +17

Proceedings of the National Academy of Sciences

Unique Multicomponent VaccineImmunologyImmunodominanceBacterial PathogensProtein-based Vaccines +19

Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment

Ulrich Vogel, Muhamed‐Kheir Taha, Julio A. Vázquez, +33

The Lancet Infectious Diseases

VaccinationVaccine SafetyPreventive MedicineReverse VaccinologyVaccine Efficacy +8

The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect

Samuele Calabrό, Elaine Tritto, Annamaria Pezzotti, +7

Vaccine

AllergyMedicineAdjuvant EffectMicroemulsionComparable Adjuvant Effect +3

Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays

Renata Grifantini, Erika Bartolini, Alessandro Muzzi, +14

Nature Biotechnology

VaccinationUnrecognized Vaccine CandidatesReverse VaccinologyVaccine DevelopmentVaccine Target +9

Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of<i>Neisseria meningitidis</i>group B

Renata Grifantini, Shite Sebastian, Elisabetta Frigimelica, +6

Proceedings of the National Academy of Sciences

A Second Pilus Type in <i>Streptococcus pneumoniae</i> Is Prevalent in Emerging Serotypes and Mediates Adhesion to Host Cells

Fábio Bagnoli, Monica Moschioni, Claudio Donati, +14

Journal of Bacteriology

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Transcriptome Analysis of Neisseria meningitidis in Human Whole Blood and Mutagenesis Studies Identify Virulence Factors Involved in Blood Survival

Hebert Echenique-Rivera, Alessandro Muzzi, Elena Del Tordello, +5

PLoS Pathogens

Nm PathogenesisImmunologyHost ResponseMedical MicrobiologyHuman Whole Blood +17

MF59 and Pam3CSK4 Boost Adaptive Responses to Influenza Subunit Vaccine through an IFN Type I-Independent Mechanism of Action

Elena Caproni, Elaine Tritto, Mario Cortese, +6

The Journal of Immunology

VaccinationCross-protectionSubunit VaccineTrivalent Influenza VaccineAllergy +13