Neil J. Kallman

Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions

Kevin P. Cole, Jennifer McClary Groh, Martin D. Johnson et al. · Science · 2017 · 292 citations · Full text

Engineering, Process Development, Biomedical Engineering +16

Kilogram-Scale GMP Manufacture of Tirzepatide Using a Hybrid SPPS/LPPS Approach with Continuous Manufacturing

Michael O. Frederick, Raymond A. Boyse, Timothy M. Braden et al. · Organic Process Research & Development · 2021 · 71 citations

Purification Method, Chemical Engineering, Engineering +15

Development of an Acyl Sulfonamide Anti-Proliferative Agent, LY573636·Na

Matthew H. Yates, Neil J. Kallman, Christopher P. Ley et al. · Organic Process Research & Development · 2009 · 30 citations

Medicinal Chemistry, Carbonyl Diimidazole, Biochemistry +11

Use of Modeling and Process Analytical Technologies in the Design of a Catalytic Amination Reaction: Understanding Oxygen Sensitivity at the Lab and Manufacturing Scales

Jeremy M. Merritt, Jonas Y. Buser, Alison N. Campbell et al. · Organic Process Research & Development · 2013 · 27 citations

Engineering, Mechanistic Approach, Organic Chemistry +17

Double Heck Route to a Dibenzoxepine and Convergent Suzuki Cross-Coupling Strategy for the Synthesis of an MR Antagonist

Marvin M. Hansen, Neil J. Kallman, Thomas M. Koenig et al. · Organic Process Research & Development · 2016 · 24 citations

Combinatorial Chemistry, Mr Antagonist Ly2623091, Organic Chemistry +17