Amanda L. McClerren

Discovery and <i>in vitro</i> biosynthesis of haloduracin, a two-component lantibiotic

Amanda L. McClerren, Lisa E. Cooper, Chao Quan et al. · Proceedings of the National Academy of Sciences · 2006 · 249 citations

Life Sciences, Microbiology, Molecular Biology +17

A Formyltransferase Required for Polymyxin Resistance in Escherichia coli and the Modification of Lipid A with 4-Amino-4-deoxy-l-arabinose

Steven D. Breazeale, Anthony A. Ribeiro, Amanda L. McClerren et al. · Journal of Biological Chemistry · 2005 · 176 citations · Full text

Life Sciences, Biochemistry, Microbiology +10

A Slow, Tight-Binding Inhibitor of the Zinc-Dependent Deacetylase LpxC of Lipid A Biosynthesis with Antibiotic Activity Comparable to Ciprofloxacin

Amanda L. McClerren, Stephanie Endsley, Jason L. Bowman et al. · Biochemistry · 2005 · 156 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Structure of the LpxC deacetylase with a bound substrate-analog inhibitor

Brian E. Coggins, Xuechen Li, Amanda L. McClerren et al. · Nature Structural & Molecular Biology · 2003 · 119 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Inhibition of Lipid A Biosynthesis as the Primary Mechanism of CHIR-090 Antibiotic Activity in <i>Escherichia coli</i>

Adam W. Barb, Amanda L. McClerren, Karnem Snehelatha et al. · Biochemistry · 2007 · 108 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13