Identification of HLA-G7 as a new splice variant of the HLA-G mRNA and expression of soluble HLA-G5, -G6, and -G7 transcripts in human transfected cells

Pascale Paul, Franscisco Adrian Cabestre, El Chérif Ibrahim, +7

Human Immunology

HistocompatibilitySoluble Hla-g5ImmunogeneticsNew Splice VariantHla Immunogenetics +6

RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites

Vincent Dive, Jöel Cotton, Athanasios Yiotakis, +6

Proceedings of the National Academy of Sciences

Bioorganic ChemistryActive SitesChemical BiologyMedicinal ChemistryPhosphinic Peptide +16

Identification of Glutamate Residues Essential for Catalytic Activity and Zinc Coordination in Aminopeptidase A

Gilles Vazeux, Jiyang Wang, Pierre Corvol, +1

Journal of Biological Chemistry

RXP 407, a Selective Inhibitor of the N-Domain of Angiotensin I-Converting Enzyme, Blocks in Vivo the Degradation of Hemoregulatory Peptide Acetyl-Ser-Asp-Lys-Pro with No Effect on Angiotensin I Hydrolysis

Christophe Junot, Marie-Françoise Gonzales, Éric Ezan, +8

Journal of Pharmacology and Experimental Therapeutics

Selective Inhibition of the C-Domain of Angiotensin I Converting Enzyme by Bradykinin Potentiating Peptides

Jöel Cotton, Mirian A.F. Hayashi, Philippe Cuniasse, +4

Biochemistry

Selective InhibitionMedicinal ChemistryAce MutantsBiochemistryNatural Sciences +11

A glutamate residue contributes to the exopeptidase specificity in aminopeptidase A

Gilles Vazeux, Xavier Iturrioz, Pierre Corvol, +1

Biochemical Journal

Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure

Xavier Iturrioz, Gilles Vazeux, M C Fournié-Zaluski, +4

Biochemical Society Transactions

A tyrosine residue essential for catalytic activity in aminopeptidase A

Gilles Vazeux, Xavier Iturrioz, Pierre Corvol, +1

Biochemical Journal

Molecular BiologyChemical BiologyProtein FoldingCatalytic ActivityStructure-function Enzyme Kinetics +15

Histidine 450 Plays a Critical Role in Catalysis and, with Ca²⁺, Contributes to the Substrate Specificity of Aminopeptidase A

Xavier Iturrioz, Gilles Vazeux, Jérôme Célérier, +2

Biochemistry

Aminopeptidase ACellular EnzymologyBiochemistryGlutamate ThiolCa2+ Ion +13

Potent and Selective Inhibition of Zinc Aminopeptidase A (EC 3.4.11.7, APA) by Glutamyl Aminophosphinic Peptides:  Importance of Glutamyl Aminophosphinic Residue in the P₁ Position

Dimitris Georgiadis, Gilles Vazeux, Catherine Llorens‐Cortés, +2

Biochemistry