Kayleigh R. McGovern-Gooch

Finely tuned conformational dynamics regulate the protective function of the lncRNA MALAT1 triple helix

Abeer A. Ageeli, Kayleigh R. McGovern-Gooch, Magdalena M Kaminska et al. · Nucleic Acids Research · 2018 · 48 citations · Full text

Conformational Dynamics, Molecular Biology, Protective Function +16

The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation

Maria B. Campaña, Flaviyan Jerome Irudayanathan, Tasha R. Davis et al. · Journal of Biological Chemistry · 2019 · 32 citations · Full text

Synthetic Triterpenoid Inhibition of Human Ghrelin <i>O</i>-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation

Kayleigh R. McGovern-Gooch, Nivedita S. Mahajani, Ariana Garagozzo et al. · Biochemistry · 2017 · 30 citations · Full text

Ghrelin Maturation, Synthetic Triterpenoid Inhibition, Chemical Biology +16

Ghrelin Octanoylation Is Completely Stabilized in Biological Samples by Alkyl Fluorophosphonates

Kayleigh R. McGovern-Gooch, Trevor Rodrigues, Joseph E. Darling et al. · Endocrinology · 2016 · 21 citations · Full text

Molecular Biology, Biological Samples, Chemical Biology +18

The octanoylated energy regulating hormone ghrelin: An expanded view of ghrelin’s biological interactions and avenues for controlling ghrelin signaling

Elizabeth R. Cleverdon, Kayleigh R. McGovern-Gooch, James L. Hougland · Molecular Membrane Biology · 2016 · 15 citations

Hormone Ghrelin, Expanded View, Insulin Signaling +22