Interleukin 21–Induced Granzyme B–Expressing B Cells Infiltrate Tumors and Regulate T Cells

Stefanie Lindner, Karen Dahlke, Kai Sontheimer, +14

Cancer Research

Human B Cells Secrete Granzyme B When Recognizing Viral Antigens in the Context of the Acute Phase Cytokine IL-21

Magdalena Hagn, Elisabeth Schwesinger, Verena Ebel, +8

The Journal of Immunology

Human B cells differentiate into granzyme B‐secreting cytotoxic B lymphocytes upon incomplete T‐cell help

Magdalena Hagn, Kai Sontheimer, Karen Dahlke, +12

Immunology and Cell Biology

Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway

Magdalena Hagn, Bernd Jahrsdörfer

OncoImmunology

Lymphocyte DevelopmentHumoral ResponseImmunologyImmune RegulationImmunologic Mechanism +18

CD5⁺ B cells from individuals with systemic lupus erythematosus express granzyme B

Magdalena Hagn, Verena Ebel, Kai Sontheimer, +11

European Journal of Immunology

Clinical ImmunologyImmune RegulationImmunologyImmunologic MechanismImmunotherapy +16

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

Olivia Susanto, Sarah E. Stewart, Ilia Voskoboinik, +8

Cell Death and Differentiation

Knockout MouseMitophagyGranzyme B-induced ApoptosisApoptosisImmunology +7

Activated Mouse B Cells Lack Expression of Granzyme B

Magdalena Hagn, Gabrielle T. Belz, Axel Kallies, +5

The Journal of Immunology

Grb ExpressionAdaptive Immune SystemHumoral ResponseImmunologyImmune Regulation +21

B cell‐derived circulating granzyme B is a feature of acute infectious mononucleosis

Magdalena Hagn, Archana Panikkar, Corey Smith, +4

Clinical & Translational Immunology

Humoral ResponseImmunologyBlood CellPathologyImmunologic Mechanism +16

B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21

Magdalena Hagn, Sue Blackwell, Thamara Beyer, +11

International Immunology

Cpg OdnApoptosisImmunologyImmune RegulationCell Death +21

A Method for Detecting Intracellular Perforin in Mouse Lymphocytes

A. J. Brennan, Imran G. House, Jane Oliaro, +5

The Journal of Immunology

Immunocytochemical TechniqueDetecting Intracellular PerforinImmunologyCell DeathPathology +18