Peter D. Smith

Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor

M. Raymond V. Finlay, Mark J. Anderton, Susan Ashton et al. · Journal of Medicinal Chemistry · 2014 · 590 citations · Full text

Genetics, Pathology, Clinical Candidate +18

Asymmetric routes to substituted piperidines

Patrick D. Bailey, Paula A. Millwood, Peter D. Smith · Chemical Communications · 1998 · 328 citations

Combinatorial Chemistry, Bioorganic Chemistry, Chiral Pool +13

Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR)

Richard A. Ward, Mark J. Anderton, Susan Ashton et al. · Journal of Medicinal Chemistry · 2013 · 257 citations · Full text

Covalent Inhibitors, Drug Target, Thiol Reactivity +19

Exploiting a fast neutron mutant genetic resource in Pisum sativum (pea) for functional genomics

Claire Domoney, M. R. Knox, Carol Moreau et al. · Functional Plant Biology · 2013 · 43 citations · Full text

Plant Genetics, Genetics, Molecular Genetics +17

Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat

James S. Scott, Andrew Bailey, Robert D. M. Davies et al. · ACS Medicinal Chemistry Letters · 2015 · 42 citations · Full text

Medicinal Chemistry, Oral Bioavailability, Tetrahydroisoquinoline Phenols +11