Identification of Therapeutic Covariant MicroRNA Clusters in Hypoxia-Treated Cardiac Progenitor Cell Exosomes Using Systems Biology

Warren D. Gray, Kristin M. French, Shohini Ghosh-Choudhary, +5

Circulation Research

Experimental, Systems, and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell–Derived Exosomes From Pediatric Patients

Udit Agarwal, Alex George, Srishti Bhutani, +8

Circulation Research

Knockdown of TNF-α by DNAzyme gold nanoparticles as an anti-inflammatory therapy for myocardial infarction

Inthirai Somasuntharam, Kevin Yehl, Sheridan L. Carroll, +6

Biomaterials

NanoparticlesNanomedicineInflammationAnti-inflammatory TherapyNanotherapeutics +10

IP₃receptor-dependent Ca²⁺release modulates excitation-contraction coupling in rabbit ventricular myocytes

Timothy L. Domeier, Aleksey V. Zima, Joshua T. Maxwell, +3

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleSynaptic TransmissionCellular PhysiologyMuscle PhysiologyAffinity Trap +16

Refractoriness of sarcoplasmic reticulum Ca²⁺ release determines Ca²⁺ alternans in atrial myocytes

Vyacheslav M. Shkryl, Joshua T. Maxwell, Timothy L. Domeier, +1

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleCellular PhysiologyHyperpolarization (Biology)Cardiac AlternansRestitution Curve +16

Dantrolene prevents arrhythmogenic Ca²⁺release in heart failure

Joshua T. Maxwell, Timothy L. Domeier, Lothar A. Blatter

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleHeart FailureCardiovascular PharmacologyCardiovascular FunctionCellular Physiology +16

The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle

Jennifer Q. Kwong, Jiuzhou Huo, Michael J. Bround, +10

JCI Insight

Muscle FunctionMitochondrial BiologyMuscle PhysiologySkeletal MuscleBioenergetics +17

Inositol‐1,4,5‐trisphosphate induced Ca²⁺ release and excitation–contraction coupling in atrial myocytes from normal and failing hearts

Felix Hohendanner, Stefanie Walther, Joshua T. Maxwell, +5

The Journal of Physiology

A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses

Marcela K. Preininger, Rajneesh Jha, Joshua T. Maxwell, +10

Disease Models & Mechanisms

Cardiac MuscleHeart FailureHuman Pluripotent StemCardiovascular PharmacologyControl Ipsc-cms +17

Aggregation of Child Cardiac Progenitor Cells Into Spheres Activates Notch Signaling and Improves Treatment of Right Ventricular Heart Failure

David Trac, Joshua T. Maxwell, Milton E. Brown, +2

Circulation Research