Danielle Hedeen

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity

Ishan Deshpande, Jiahao Liang, Danielle Hedeen et al. · Nature · 2019 · 208 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β

Ken Tawara, H. Scott, Jacqueline Emathinger et al. · Oncotarget · 2019 · 68 citations · Full text

Medicine, Immunology, Oncology +17

Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits

Corvin D. Arveseth, John T. Happ, Danielle Hedeen et al. · PLoS Biology · 2021 · 68 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction

John T. Happ, Corvin D. Arveseth, Jessica Bruystens et al. · Nature Structural & Molecular Biology · 2022 · 65 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Co-Expression of VEGF and IL-6 Family Cytokines is Associated with Decreased Survival in HER2 Negative Breast Cancer Patients: Subtype-Specific IL-6 Family Cytokine-Mediated VEGF Secretion

Ken Tawara, H. Scott, Jacqueline Emathinger et al. · Translational Oncology · 2018 · 59 citations · Full text

Medicine, Cancer Biology, Oncology +17