Danielle Hedeen

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity

Ishan Deshpande, Jiahao Liang, Danielle Hedeen et al. · Nature · 2019 · 204 citations · Full text

Signal Transduction, Oxysterol, Physiology +7

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β

Ken Tawara, H. Scott, Jacqueline Emathinger et al. · Oncotarget · 2019 · 66 citations · Full text

Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits

Corvin D. Arveseth, John T. Happ, Danielle Hedeen et al. · PLoS Biology · 2021 · 64 citations · Full text

Activity-dependent Sequestration, Signal Transduction, Developmental Biology +15

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction

John T. Happ, Corvin D. Arveseth, Jessica Bruystens et al. · Nature Structural & Molecular Biology · 2022 · 59 citations · Full text

Hedgehog Signal Transduction, Developmental Biology, Molecular Physiology +7

Co-Expression of VEGF and IL-6 Family Cytokines is Associated with Decreased Survival in HER2 Negative Breast Cancer Patients: Subtype-Specific IL-6 Family Cytokine-Mediated VEGF Secretion

Ken Tawara, H. Scott, Jacqueline Emathinger et al. · Translational Oncology · 2018 · 58 citations · Full text

Breast Oncology, Immunology, Pathology +20