Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer

Yann Kieffer, Hocine R. Hocine, Géraldine Gentric, +13

Cancer Discovery

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers

Géraldine Gentric, Yann Kieffer, Virginie Mieulet, +15

Cell Metabolism

Metabolic RemodelingHuman Ovarian CancersRedox BiologyTumor BiologyOxidative Stress +14

miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers

Anne-Marie Givel, Yann Kieffer, Alix Scholer‐Dahirel, +10

Nature Communications

Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease

Géraldine Gentric, Vanessa Maillet, Valérie Paradis, +6

Journal of Clinical Investigation

PathologyCell CycleFatty Liver DiseaseOxidative StressInflammation +20

Deciphering the spatial landscape and plasticity of immunosuppressive fibroblasts in breast cancer

Hugo Croizer, Rana Mhaidly, Yann Kieffer, +13

Nature Communications

Polyploidy spectrum: a new marker in HCC classification

Myriam Bou-Nader, Stefano Caruso, Romain Donné, +13

Gut

Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers

Rania El Botty, Ludivine Morriset, Élodie Montaudon, +24

Nature Communications

Hepatocytes Polyploidization and Cell Cycle Control in Liver Physiopathology

Géraldine Gentric, Chantal Desdouets, Séverine Celton‐Morizur

International Journal of Hepatology

Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate

Judith Goncalves, Sophie Moog, Aurélie Morin, +17

Cancer Research

AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression

Grégory Merlen, Géraldine Gentric, Séverine Celton‐Morizur, +6

Journal of Hepatology

Signal TransductionHepatologyMolecular PhysiologyEnergy BalanceCell Regulation +11