Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

Oscar P. B. Wiklander, Joel Z. Nordin, Aisling J. O’Loughlin, +14

Journal of Extracellular Vesicles

Cell SourceEngineeringImmunologyPathologyExtracellular Microvesicles +20

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

Joel Z. Nordin, Yi Lee, Pieter Vader, +15

Nanomedicine Nanotechnology Biology and Medicine

Systemic exosomal siRNA delivery reduced alpha‐synuclein aggregates in brains of transgenic mice

Jonathan M. Cooper, Oscar P. B. Wiklander, Joel Z. Nordin, +7

Movement Disorders

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

Oscar P. B. Wiklander, Rakibe Beklem Bostancıoğlu, Joshua A Welsh, +19

Frontiers in Immunology

PathologyImmunophenotypingCell CultureFlow CellCytoskeleton +16

Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

Giulia Corso, Imre Mäger, Yi Lee, +6

Scientific Reports

Protein SecretionImmunocytochemical TechniqueExtracellular MicrovesiclesAnalytical UltracentrifugationSize Exclusion Chromatography +17

Quantification of extracellular vesicles <i>in vitro</i> and <i>in vivo</i> using sensitive bioluminescence imaging

Dhanu Gupta, Xiuming Liang, Oscar P. B. Wiklander, +17

Journal of Extracellular Vesicles

Serum‐free culture alters the quantity and protein composition of neuroblastoma‐derived extracellular vesicles

Jinghuan Li, Yi Lee, Henrik J. Johansson, +7

Journal of Extracellular Vesicles

Extracellular FactorsProtein CompositionImmunologyCell CultureExtracellular Microvesicles +17

Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging

Giulia Corso, Wolf Heusermann, Dominic Trojer, +11

Journal of Extracellular Vesicles

Proteinlipid InteractionMolecular BiologyExtracellular MicrovesiclesSingle VesiclesSingle Molecule Biophysics +20

Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice

Audrey Jalabert, Guillaume Vial, Claudiane Guay, +13

Diabetologia

Extracellular MicrovesiclesCytoskeletonLipid-induced Insulin-resistant MusclesCellular PhysiologyInsulin Signaling +14

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

Oscar E. Simonson, Dimitrios Mougiakakos, Nina Heldring, +25

Stem Cells Translational Medicine