Jiachuan Jin

The post-PAM interaction of RNA-guided spCas9 with DNA dictates its target binding and dissociation

Qian Zhang, Fengcai Wen, Siqi Zhang et al. · Science Advances · 2019 · 56 citations · Full text

m⁶A reader protein YTHDF2 regulates spermatogenesis by timely clearance of phase‐specific transcripts

Meijie Qi, Haifeng Sun, Yueshuai Guo et al. · Cell Proliferation · 2021 · 41 citations · Full text

Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer

Qian Zhang, Ziting Chen, Fangzhu Wang et al. · Nucleic Acids Research · 2021 · 16 citations · Full text

A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon

Lei Tan, Xiaolong Qi, Weining Kong et al. · Science Advances · 2023 · 16 citations · Full text

Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity

Kai Cheng, Li Cao, Jiachuan Jin et al. · Molecular Therapy — Nucleic Acids · 2023 · 14 citations · Full text