Christophe Klein

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy, Emmanuelle Le Chatelier, Lisa Derosa et al. · Science · 2017 · 5.2K citations

Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells

Jérémy Goc, Claire Germain, Thi Kim Duy Vo-Bourgais et al. · Cancer Research · 2013 · 621 citations

T-regulatory Cell, Immunology, Pathology +20

Prognostic Value of Tumor-Infiltrating CD4+ T-Cell Subpopulations in Head and Neck Cancers

Cécile Badoual, Stéphane Hans, José Rodriguez et al. · Clinical Cancer Research · 2006 · 589 citations

Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.

Christophe Klein, D. Dressel, T Steinmayer et al. · The Journal of Cell Biology · 1991 · 354 citations · Full text

Tissue Engineering, Collagen Matrices, Engineering +22

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

Nicolas Jacquelot, Takahiro Yamazaki, María P. Roberti et al. · Cell Research · 2019 · 238 citations · Full text