Essential Role forSonic hedgehogduring Hair Follicle Morphogenesis

Chin Chiang, Ryan Z. Swan, Marina Grachtchouk, +8

Developmental Biology

Hair Follicle MorphogenesisDevelopmental BiologyOogenesisMorphogenesisEmbryonic Development +4

Basal cell carcinomas in mice overexpressing Gli2 in skin

Marina Grachtchouk, Rong Mo, Sandy Yu, +4

Nature Genetics

Cutaneous BiologyDermatologyMedicineCancer ResearchTumor Biology +2

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development

Pleasantine Mill, Rong Mo, Hong En Fu, +4

Genes & Development

Gli Transcription FactorsGeneticsCell ProliferationReproductive BiologyDermatology +15

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle

Mark E. Hutchin, Muhammed S.T. Kariapper, Marina Grachtchouk, +7

Genes & Development

Lineage PlasticityDevelopmental BiologySkin CancerMedicineCutaneous Biology +13

Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations

Marina Grachtchouk, Joanna Pero, Steven Yang, +12

Journal of Clinical Investigation

Cell ProliferationSuperficial BccsDermatologyBasal Cell CarcinomaNodular Bcc Development +18

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes

Monica Dentice, Cristina Luongo, Stephen A. Huang, +12

Proceedings of the National Academy of Sciences

Bcc XenograftsCell ProliferationDermatologySonic HedgehogTumor Biology +16

A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

Erich Roessler, Alexandre N. Ermilov, Dorothy K. Grange, +4

Human Molecular Genetics

Hedgehog Signaling Regulates Sebaceous Gland Development

Mary C. Allen, Marina Grachtchouk, Hong Sheng, +9

American Journal Of Pathology

Skin DevelopmentCell LineageDevelopmental BiologyMorphogenesisMedicine +3

Obesity accelerates hair thinning by stem cell-centric converging mechanisms

Hironobu Morinaga, Yasuaki Mohri, Marina Grachtchouk, +13

Nature

Lineage PlasticityDevelopmental BiologyMedicineAdult Stem CellMorphogenesis +4

Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance

Hong Xiang Liu, Alexandre N. Ermilov, Marina Grachtchouk, +4

Developmental Biology

BiologyFungal Developmental BiologyDevelopmental BiologySignal TransductionTaste Bud Formation +10