Jean Binet

Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate

Benaı̈ssa Boubia, Olivia Poupardin, Martine Barth et al. · Journal of Medicinal Chemistry · 2018 · 106 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +19

Synthesis of a series of compounds related to betaxolol, a new .beta.1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases

P. Manoury, Jean Binet, Jean L.C. Rousseau et al. · Journal of Medicinal Chemistry · 1987 · 67 citations · Full text

Hypertension, Cardiovascular Pharmacology, Chronic Cardiovascular Diseases +16

Synthesis and antihypertensive activity of a series of 4-amino-6,7-dimethoxyquinazoline derivatives

P. Manoury, Jean Binet, Andre P. Dumas et al. · Journal of Medicinal Chemistry · 1986 · 50 citations

Preferential pharmacological inhibition of macrophage ACAT increases plaque formation in mouse and rabbit models of atherogenesis

Stéphane Perrey, Christiane Legendre, Akihiro Matsuura et al. · Atherosclerosis · 2001 · 47 citations

Inflammation, Cytokine, Autophagy +11

Structural and Stereoelectronic Requirements for the Inhibition of Mammalian 2,3-Oxidosqualene Cyclase by Substituted Isoquinoline Derivatives

Martine Barth, Jean Binet, Didier M. Thomas et al. · Journal of Medicinal Chemistry · 1996 · 25 citations · Full text

Bioorganic Chemistry, Organic Chemistry, Heterocycle Chemistry +20