Laura McEntee

F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase

Jason D. Oliver, Graham E. M. Sibley, Nicola Beckmann et al. · Proceedings of the National Academy of Sciences · 2016 · 269 citations · Full text

Dihydroorotate Dehydrogenase, Bioorganic Chemistry, Pyrimidine Biosynthesis +18

Pharmacodynamics of the Orotomides against <i>Aspergillus fumigatus</i> : New Opportunities for Treatment of Multidrug-Resistant Fungal Disease

William Hope, Laura McEntee, Joanne Livermore et al. · mBio · 2017 · 73 citations · Full text

<i>In Vitro</i> Susceptibility of Aspergillus fumigatus to Isavuconazole: Correlation with Itraconazole, Voriconazole, and Posaconazole

Lea Gregson, Joanne Goodwin, Adam Johnson et al. · Antimicrobial Agents and Chemotherapy · 2013 · 70 citations · Full text

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance

William Hope, Neil Stone, Adam Johnson et al. · mBio · 2019 · 70 citations · Full text

Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus

C. E. Negri, Adam Johnson, Laura McEntee et al. · The Journal of Infectious Diseases · 2017 · 58 citations · Full text