Mengru Gu

The signaling protein Wnt5a promotes TGFβ1-mediated macrophage polarization and kidney fibrosis by inducing the transcriptional regulators Yap/Taz

Feng Ye, Yan Liang, Xingwen Zhu et al. · Journal of Biological Chemistry · 2018 · 143 citations · Full text

Kidney Fibrosis, Renal Pathology, Immunology +18

Rheb1 protects against cisplatin-induced tubular cell death and acute kidney injury via maintaining mitochondrial homeostasis

Qingmiao Lu, Mingjie Wang, Yuan Gui et al. · Cell Death and Disease · 2020 · 61 citations · Full text

Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation

Mengru Gu, Hanlu Jiang, Mengzhu Tan et al. · Nature Communications · 2023 · 55 citations · Full text

Renal Pathology, Renal Inflammation, Protein Palmitoylation +23

Protein phosphatase 2Acα modulates fatty acid oxidation and glycolysis to determine tubular cell fate and kidney injury

Mengru Gu, Mengzhu Tan, Lu Zhou et al. · Kidney International · 2022 · 46 citations

Tubular Cell Fate, Renal Pathology, Kidney Injury +16

Fibroblast mTOR/PPARγ/HGF axis protects against tubular cell death and acute kidney injury

Yuan Gui, Qingmiao Lu, Mengru Gu et al. · Cell Death and Differentiation · 2019 · 40 citations · Full text

Inflammation, Urology, Molecular Physiology +14