Joseph J. Senn

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

Kimberly J. Hassett, Kerry E. Benenato, Eric Jacquinet et al. · Molecular Therapy — Nucleic Acids · 2019 · 888 citations · Full text

Pharmacy, Immunology, Pharmaceutics +17

Interleukin-6 Induces Cellular Insulin Resistance in Hepatocytes

Joseph J. Senn, Peter Klover, Irena Nowak et al. · Diabetes · 2002 · 877 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates

Staci Sabnis, E. Sathyajith Kumarasinghe, Timothy Salerno et al. · Molecular Therapy · 2018 · 794 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +16

Suppressor of Cytokine Signaling-3 (SOCS-3), a Potential Mediator of Interleukin-6-dependent Insulin Resistance in Hepatocytes

Joseph J. Senn, Peter Klover, Irena Nowak et al. · Journal of Biological Chemistry · 2003 · 614 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17

mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials

Robert Feldman, Rainard Fuhr, Igor Smolenov et al. · Vaccine · 2019 · 463 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17