Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis

Eliane M.S. Leyten, May Young Lin, Kees L. M. C. Franken, +10

Microbes and Infection

Pulmonary TuberculosisT-regulatory CellPathogenesisImmunologyMycobacterium Tuberculosis +10

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human

Jaap T. van Dissel, Simone A. Joosten, Søren T. Hoff, +13

Vaccine

T-regulatory CellInnate Immune SystemImmune RegulationImmunologyImmunologic Mechanism +15

Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

Jaap T. van Dissel, Sandra M. Arend, Corine Prins, +10

Vaccine

Pulmonary TuberculosisAdaptive Immune SystemMedicineImmunologyTuberculosis +6

Mycobacterial growth inhibition is associated with trained innate immunity

Simone A. Joosten, Krista E. van Meijgaarden, Sandra M. Arend, +8

Journal of Clinical Investigation

Protection Hampers DevelopmentAdaptive Immune SystemInnate Immune SystemImmunologyImmune Regulation +16

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19

Anna H.E. Roukens, Cilia R. Pothast, Marion König, +94

Nature Immunology

Adaptive Immune SystemImmunologyProlonged ActivationT Cell ImmunityCd4 T Cell Responses +5

Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection

Jaap T. van Dissel, Darius Soonawala, Simone A. Joosten, +12

Vaccine

Pulmonary TuberculosisTuberculosis PreventionImmunologyPrevious Bcg VaccinationTuberculosis +6

Discrepancy between <i>Mycobacterium tuberculosis</i> -Specific Gamma Interferon Release Assays Using Short and Prolonged In Vitro Incubation

Eliane M.S. Leyten, Sandra M. Arend, Corine Prins, +3

Clinical and Vaccine Immunology

Pulmonary TuberculosisQft-git TestVitro IncubationElispot ResultsTuberculosis Prevention +10

An Unbiased Genome-Wide <i>Mycobacterium tuberculosis</i> Gene Expression Approach To Discover Antigens Targeted by Human T Cells Expressed during Pulmonary Infection

Susanna Commandeur, Krista E. van Meijgaarden, Corine Prins, +12

The Journal of Immunology

Tuberculosis PreventionImmunologyDiscover AntigensCd4 T Cell ResponsesImmune System +17

Effect of tuberculin skin testing on a<i>Mycobacterium tuberculosis</i>-specific interferon-γ assay

Eliane M.S. Leyten, Corine Prins, Aik Bossink, +4

European Respiratory Journal

New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles

Mariateresa Coppola, Krista E. van Meijgaarden, Kees L. M. C. Franken, +12

Scientific Reports