Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease

Alain R. Simard, Denis Soulet, Genevíève Gowing, +2

Neuron

InflammationMarrow-derived Microglia PlayAlzheimer's DiseaseMedicineDementia +10

Selective Ablation of Proliferating Microglial Cells Exacerbates Ischemic Injury in the Brain

Mélanie Lalancette–Hébert, Genevíève Gowing, Alain R. Simard, +2

Journal of Neuroscience

Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia

Alain R. Simard, Serge Rivest

The FASEB Journal

Cell TherapyAdult Stem CellImmunologyGliomaNeuroinflammation +20

A Novel Nicotinic Acetylcholine Receptor Subtype in Basal Forebrain Cholinergic Neurons with High Sensitivity to Amyloid Peptides

Qiang Liu, Yao‐Kuang Huang, Fenqin Xue, +11

Journal of Neuroscience

Nerve Activity-dependent Modulation of Calcineurin Signaling in Adult Fast and Slow Skeletal Muscle Fibers

Shannon E. Dunn, Alain R. Simard, Rhonda Bassel‐Duby, +2

Journal of Biological Chemistry

Muscle FunctionCytoskeletonMechanotransductionCalcineurin SignalingPeripheral Nerve +21

Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis

Zhenzhen Ge, Yurong Da, Zhenyi Xue, +9

Experimental Neurology

Autoimmune DiseaseHistone Deacetylase InhibitorMedicineAutophagyImmunology +10

Medroxyprogesterone acetate impairs memory and alters the GABAergic system in aged surgically menopausal rats

B. Blair Braden, Joshua S. Talboom, Ian D. Crain, +6

Neurobiology of Learning and Memory

AgingGabaergic SystemPhysiologyNeuroendocrine MechanismMenopausal Rats +5

Attenuation of CNS inflammatory responses by nicotine involves α7 and non-α7 nicotinic receptors

Junwei Hao, Alain R. Simard, Gregory Turner, +4

Experimental Neurology

InflammationMolecular PharmacologyNon-α7 Nicotinic ReceptorsCns Inflammatory ResponsesNeurophysiology +11

Neuroprotective effects of resident microglia following acute brain injury

Alain R. Simard, Serge Rivest

The Journal of Comparative Neurology

Nicotinic Acetylcholine Receptors Modulate Bone Marrow-Derived Pro-Inflammatory Monocyte Production and Survival

Stéphanie St‐Pierre, Wei Jiang, Patrick Roy, +5

PLoS ONE

Inflammatory Lung DiseaseLung InflammationImmunologyImmune RegulationCell Death +23