iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer

Dong Shin Park, Tatsuya Kozaki, Satish Kumar Tiwari, +54

Nature

InflammationMedicineCerebral OrganoidBrain-immune InteractionNeuroscience +4

Microplastics released from food containers can suppress lysosomal activity in mouse macrophages

Jingyu Deng, Mohammed Shahrudin Ibrahim, Li Yang Tan, +7

Journal of Hazardous Materials

MedicineFood ContainersPathogenesisAutophagyMouse Macrophages +5

Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes

Xiaofeng Zheng, Qing Wei Calvin Ho, Minni Chua, +16

Proceedings of the National Academy of Sciences

Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome

Kagistia Hana Utami, Niels H. Skotte, Ana R. Colaço, +16

Biological Psychiatry

Neurodevelopmental DisordersFragile X SyndromeMolecular NeuroscienceDevelopmental BiologyMendelian Disorder +11

A neural circuit for excessive feeding driven by environmental context in mice

Hasan Mohammad, Esra Senol, Martin Graf, +11

Nature Neuroscience

Environmental ContextSocial SciencesNeuroendocrine MechanismExcessive FeedingAppetite Control +14

Plant‐Based Shape Memory Cryogel for Hemorrhage Control

Jingyu Deng, Ze Zhao, Xin Yi Yeo, +8

Advanced Materials

Tissue EngineeringNanomedicineBiofunctional MaterialBiocompatible MaterialEngineering +11

Unique dynamics and exocytosis properties of GABAergic synaptic vesicles revealed by three-dimensional single vesicle tracking

Chungwon Park, Xingxiang Chen, Chong-Li Tian, +8

Proceedings of the National Academy of Sciences

Exocytosis PropertiesSynaptic TransmissionExtracellular MicrovesiclesCytoskeletonNeurotransmission +21

Mapping Drug-Induced Neuropathy through In-Situ Motor Protein Tracking and Machine Learning

Zhigao Yi, Huxin Gao, Xianglin Ji, +11

Journal of the American Chemical Society

EngineeringMachine LearningDrug-induced NeuropathyNeurochemical BiomarkersDynamic Near-infrared Upconversion +14

Stromal vascular fraction promotes fibroblast migration and cellular viability in a hyperglycemic microenvironment through up-regulation of wound healing cytokines

Shaun Shi Yan Tan, Xin Yi Yeo, Zhen Liang, +2

Experimental and Molecular Pathology

InflammationRegenerative MedicineCellular ViabilityAngiogenesisHyperglycemic Microenvironment +12

Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult

Amin Ziaei, Marta Garcia‐Miralles, Carola I. Radulescu, +20

Brain Pathology