Karen Siegler

Sitosterolemia in ABC-Transporter G5-deficient mice is aggravated on activation of the liver-X receptor

Torsten Plösch, Vincent W. Bloks, Yuko Terasawa et al. · Gastroenterology · 2003 · 150 citations · Full text

Life Sciences, Endocrinology, Physiology +11

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo

Alykhan Motani, Zhulun Wang, Marion Conn et al. · Journal of Biological Chemistry · 2009 · 79 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Identification of a PPARδ agonist with partial agonistic activity on PPARγ

Richard Connors, Zhulun Wang, Martin Harrison et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 41 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2α phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic

Haruki Hasegawa, Ann Hsu, Christine E. Tinberg et al. · mAbs · 2017 · 17 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists

Ming Yu, Jian Zhang, Yingcai Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12