DPA-714, a New Translocator Protein–Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

Michelle L. James, Roger Fulton, Johnny Vercoullie, +7

Journal of Nuclear Medicine

Behavior and serotonergic disorders in rats exposed prenatally to valproate: A model for autism

Diane Dufour‐Rainfray, Patrick Vourc’h, Anne‐Marie Le Guisquet, +9

Neuroscience Letters

PsychiatryBehavioral NeuroscienceSerotonergic DisordersMedicineSyndromic Autism +10

Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease

Gaëlle Bouchez, Luc Sensebé, Patrick Vourc’h, +7

Neurochemistry International

Regenerative MedicineDopaminergic PathwayPartial RecoveryMedicineStem Cell Transplantation +9

Synthesis and Ligand Binding of Nortropane Derivatives:  N-Substituted 2β-Carbomethoxy-3β-(4‘-iodophenyl)nortropane and <i>N</i>-(3-Iodoprop-(2<i>E</i>)-enyl)-2β-carbomethoxy-3β-(3‘,4‘-disubstituted phenyl)nortropane. New High-Affinity and Selective Compounds for the Dopamine Transporter

Patrick Emond, Lucette Garreau, Sylvie Chalon, +7

Journal of Medicinal Chemistry

Exploration of the Dopamine Transporter: In Vitro and In Vivo Characterization of a High-Affinity and High-Specificity Iodinated Tropane Derivative (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy- 3β-(4′-methylphenyl)nortropane (PE2I)

Denis Guilloteau, Patrick Emond, Jean‐Louis Baulieu, +6

Nuclear Medicine and Biology

Molecular PharmacologyVivo CharacterizationBiochemistryDopamine TransporterMedicine +12

Pharmacological characterization of (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-methylphenyl)n ortropane as a selective and potent inhibitor of the neuronal dopamine transporter.

Sylvie Chalon, Lucette Garreau, Patrick Emond, +4

PubMed

Pharmacological CharacterizationNeuronal Dopamine TransporterPotent InhibitorNeurotransmitterPharmacotherapy +17

Pharmacological Characterization of N,N-Dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a Ligand of the Serotonin Transporter with High Affinity and Selectivity

Sylvie Chalon, Jari Tarkiainen, Lucette Garreau, +9

Journal of Pharmacology and Experimental Therapeutics

Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation

Nicolas Arlicot, Andrew Katsifis, Lucette Garreau, +3

European Journal of Nuclear Medicine and Molecular Imaging

InflammationMicroglial ActivationCellular NeuroscienceMedicineBrain-immune Interaction +8

Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study

Sophie Sérrière, Clovis Tauber, Johnny Vercouillie, +8

Neurobiology of Aging

Neurodegenerative DiseasesAppsweps1-de9 MiceAlzheimer's DiseaseImmunologyDegenerative Pathology +6

Pharmacological Characterization of (E)-N-(4-Fluorobut-2-enyl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane (LBT-999) as a Highly Promising Fluorinated Ligand for the Dopamine Transporter

Sylvie Chalon, Håkan Hall, Wadad Saba, +12

Journal of Pharmacology and Experimental Therapeutics