PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival

Georgios Batsios, Pavithra Viswanath, Elavarasan Subramani, +6

Scientific Reports

Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas

Pavithra Viswanath, Georgios Batsios, Vinay Ayyappan, +7

Neuro-Oncology

Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer

Georgios Batsios, Céline Taglang, Meryssa Tran, +6

Clinical Cancer Research

Non-invasive assessment of telomere maintenance mechanisms in brain tumors

Pavithra Viswanath, Georgios Batsios, Joydeep Mukherjee, +7

Nature Communications

Hybrid multiband excitation multiecho acquisition for hyperpolarized ¹³C spectroscopic imaging

Andreas Sigfridsson, Kilian Weiss, Lukas Wissmann, +6

Magnetic Resonance in Medicine

MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma

Abigail R. Molloy, Chloé Najac, Pavithra Viswanath, +7

Theranostics

Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas

Céline Taglang, Georgios Batsios, Joydeep Mukherjee, +7

Neuro-Oncology

In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine

Georgios Batsios, Chloé Najac, Peng Cao, +8

Scientific Reports

Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment

Elavarasan Subramani, Marina Radoul, Chloé Najac, +9

Cancer Research

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone

Georgios Batsios, Céline Taglang, Peng Cao, +8

Frontiers in Oncology